A Dual-Ingredient Antiparasitic Combination

The Ivermectin + Mebendazole capsule combines two well-studied antiparasitic medicines into a single formula — 25mg Ivermectin and 250mg Mebendazole per capsule. Each is an FDA-approved active pharmaceutical ingredient with decades of clinical use. This is not a supplement or a "cleanse" powder. It is a compounded prescription medication, prepared by Pharmacy Hub LLC, a U.S. compounding pharmacy licensed in all 50 states, against an active prescription. Whether this medication is appropriate for you is determined by a licensed provider.

About Ivermectin

Ivermectin is an antiparasitic compound first described in the 1970s and used in human medicine since. It has been FDA-approved for human use since 1996. Ivermectin acts on certain channels in the nerve and muscle cells of some parasites. Its clinical use is well documented in the medical literature.

The Ivermectin in a 1776 Health capsule is human-grade, USP-quality active pharmaceutical ingredient, compounded by a licensed U.S. pharmacy and sourced from FDA-registered API suppliers, then tested for identity, potency, and purity before it is formulated.

About Mebendazole

Mebendazole has been FDA-approved since 1974 and is widely used for intestinal parasitic infections in adults and children. It belongs to the benzimidazole class. Its described mechanism differs from Ivermectin's: rather than acting on the nervous system, Mebendazole is understood to interfere with glucose uptake in parasitic worms. Pairing two ingredients with different described mechanisms is the reasoning behind the "dual-action" framing.

What "21 Days On / 21 Days Off" Means

A commonly described schedule for this combination is 21 days on, followed by 21 days off, then repeat. The rest period reflects the fact that parasite life cycles include stages that may respond differently at different times. Whether this schedule is appropriate for you, and the exact dose and frequency, is determined by your prescribing provider based on your weight and medical history.

Supply is measured in cycles, which is why the packaging refers to cycles rather than a simple day count:

• The 90-day supply (45 capsules) covers a 2-cycle course.
• The 180-day supply (90 capsules) covers a 4-cycle course.

The capsule counts describe the supply, not a self-directed dosing schedule. Your prescribing provider sets the exact dose and frequency based on your weight and medical history.

How To Take It

These capsules are for oral use only, and always exactly as prescribed by your provider. Capsule type may vary — hypromellose or bovine gelatin capsules may be used — so notify your doctor of any beef or gelatin allergies. Because dosing is individualized, the most important rule is to follow the instructions your prescribing provider gives you, not a protocol you read online.

Safety, Side Effects, And Who Should Not Take It

Like any medication, this product carries the potential for side effects. Some users may experience dizziness, nausea, diarrhea, fatigue, abdominal pain or cramps, vomiting, headache, fever, or gas. Do not take it if you have a known allergy or hypersensitivity to Ivermectin, Mebendazole, or any other component of the formulation. Significant drug interactions may exist and can require dose adjustments or avoidance, and additional considerations apply for anyone who is immunocompromised. Prolonged use of high-dose Mebendazole may cause liver impairment, neutropenia, or agranulocytosis. Consult a medical provider before use in pregnancy or breastfeeding. These are the kinds of considerations a licensed provider reviews, which is why treatment is only dispensed after a clinical review.

Why It's Compounded

Ivermectin and Mebendazole as a 25mg / 250mg combination capsule isn't stocked on retail pharmacy shelves — it's compounded for you, one prescription at a time, by Pharmacy Hub LLC, a U.S. compounding pharmacy licensed in all 50 states. Compounding is a legal, regulated pharmacy practice: it means a personalized, prescribed-for-you medication rather than a mass-produced product. It also means the combination formulation is not itself FDA-approved as a combination product, even though both active ingredients individually are. That distinction is worth understanding before you order.

The Bottom Line

The Ivermectin + Mebendazole capsule combines two FDA-approved antiparasitic ingredients into a single formula, and any use is dosed by a licensed provider. It is a compounded prescription medication — prepared for you by Pharmacy Hub LLC, a U.S. compounding pharmacy licensed in all 50 states — not an over-the-counter cleanse. Whether it is appropriate for you is determined by a licensed provider; the next step is a provider consultation.